[HTML][HTML] Deficit of mitochondria-derived ATP during oxidative stress impairs mouse MII oocyte spindles

X Zhang, XQ Wu, S Lu, YL Guo, X Ma - Cell research, 2006 - nature.com
… no effects on spindle morphology. In conclusion, the decrease in mitochondria-derived ATP
during oxidative stress may cause a disassembly of mouse MII oocyte spindles, presumably …

[HTML][HTML] Impact of oxidative stress on age-associated decline in oocyte developmental competence

H Sasaki, T Hamatani, S Kamijo, M Iwai… - Frontiers in …, 2019 - frontiersin.org
… reduces ATP synthesis and influences the meiotic spindle … , its lack of protective histones,
and deficiency of efficient repair … ) in oocytes from Drp1-deficient mice, resulting in impaired Ca …

Maternal insulin resistance causes oxidative stress and mitochondrial dysfunction in mouse oocytes

XH Ou, S Li, ZB Wang, M Li, S Quan, F Xing… - Human …, 2012 - academic.oup.com
… found that the average ATP level in GV oocytes from the INS-… examined the spindle and
chromosomes of MII oocytes from … GV and MII oocytes of insulin-resistant mice, and IR impairs

[HTML][HTML] Molecular mechanisms responsible for increased vulnerability of the ageing oocyte to oxidative damage

BP Mihalas, KA Redgrove, EA McLaughlin… - Oxidative medicine and …, 2017 - hindawi.com
… , during spindle assembly in the MI and MII phases of oocyte … the spindles in order to meet
the enhanced demand for ATP [… been shown that oxidative stress can impair the heat shock …

Melatonin protects against chronic stress-induced oxidative meiotic defects in mice MII oocytes by regulating SIRT1

Y Guo, J Sun, S Bu, B Li, Q Zhang, Q Wang, D Lai - Cell Cycle, 2020 - Taylor & Francis
… In addition, the deficit of mitochondria-derived ATP during oxidative stress impairs mouse
oocyte spindles [Citation35]. SIRT1 is also a regulator of ROS homeostasis [Citation13] and the …

Mitochondrial dynamics during mouse oocyte maturation

CM Dalton - 2011 - discovery.ucl.ac.uk
… Migration of the spindle to the oocyte cortex was accompanied by mitochondria but at polar
body … complex was found to influence ATP levels in the oocyte; oocytes matured as part of a …

Oocyte-specific deletion of Gsα induces oxidative stress and deteriorates oocyte quality in mice

Y Xie, B Wu, Y Jin, A Zhang, X Sun, X Zhang… - Experimental Cell …, 2018 - Elsevier
… G s α deficiency in oocytes leads to oxidative stress. … Meiotic spindle formation and distribution
of CGs in MII oocytes … in oocytes caused impaired developmental potential of oocytes and …

Prevention of maternal aging-associated oocyte aneuploidy and meiotic spindle defects in mice by dietary and genetic strategies

K Selesniemi, HJ Lee… - Proceedings of the …, 2011 - National Acad Sciences
oxidative stress in isolated mouse oocytes reduces ATP levels … -1α deficiency in AL-fed and
CR-AL-fed females on oocyte yield … with mouse and human oocytes showing that impaired

Impaired mitochondrial function in murine oocytes is associated with controlled ovarian hyperstimulationand in vitro maturation

H Ge, TL Tollner, Z Hu, M Da, X Li… - Reproduction …, 2012 - CSIRO Publishing
… of oocyte mitochondria, a mouse model was used. Matured … Oxidative damage also impairs
spindle and chromosome … oocytes in the IVM group had normal ATP content, the rate of …

Toxicant effects on mammalian oocyte mitochondria

KF Malott, U Luderer - Biology of Reproduction, 2021 - academic.oup.com
spindle assembly and chromosome alignment, two ATP-… MXC and rotenone induce ovarian
oxidative damage [91, 94], … and that glyphosate hinders the ability of the oocyte to effectively …